2007-11-30
psychopharmacology
How Bug Spray Works | This is here because of a search I did on "paradoxical effects" of psychiatric medications | The read is interesting and relevant since the article 
first talks about the brain's neurons communicate with one another, and how drugs affect that communication process |
Read down and you'll find that a chemical known as Acetylcholine is used by the neurons that control your muscles, heart, and lungs | It is also used by many neurons in the brain that are involved in memory | Acetylcholine crosses the brain synapses and tells the muscles to extend by stimulating the receptor sites on the muscles |
When nerve signals are terminated this is called “reuptake” | Acetylcholine is rapidly broken down by a chemical called acetylcholinesterase | Have you ever looked at the fine print on a bottle of Prozac, Paxil, or Zoloft? It says in there that the drug is a “selective serotonin reuptake inhibitor” (SSRI) |
Now, read the fine print on a can of insecticide | For some of them, it says that the active ingredient is an “acetylcholinesterase inhibitor” | So, the same effect that we see with bug spray, can be facilitated by SSRIs | You do the math |
As an FYI, nicotine directly stimulates acetylcholine receptors | Alzheimer’s disease results when these acetylcholine-using neurons in the brain die | [As an aside, does this new info about bug spray provide us any fresh insights on the actions of former insect exterminatior Tom DeLay?]
first talks about the brain's neurons communicate with one another, and how drugs affect that communication process | Read down and you'll find that a chemical known as Acetylcholine is used by the neurons that control your muscles, heart, and lungs | It is also used by many neurons in the brain that are involved in memory | Acetylcholine crosses the brain synapses and tells the muscles to extend by stimulating the receptor sites on the muscles |
When nerve signals are terminated this is called “reuptake” | Acetylcholine is rapidly broken down by a chemical called acetylcholinesterase | Have you ever looked at the fine print on a bottle of Prozac, Paxil, or Zoloft? It says in there that the drug is a “selective serotonin reuptake inhibitor” (SSRI) |
Now, read the fine print on a can of insecticide | For some of them, it says that the active ingredient is an “acetylcholinesterase inhibitor” | So, the same effect that we see with bug spray, can be facilitated by SSRIs | You do the math |
As an FYI, nicotine directly stimulates acetylcholine receptors | Alzheimer’s disease results when these acetylcholine-using neurons in the brain die | [As an aside, does this new info about bug spray provide us any fresh insights on the actions of former insect exterminatior Tom DeLay?]
Labels: brain damage, bug spray, psychopharmacology, SSRI, tom delay
¶ 03:54
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Yes, it's been known for some time that smokers have a lower risk of Alhzeimers than non-smokers and I believe nicotine formulations are being researched for their efficacy in treating the disease.
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